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Number of Sessions: Often fewer sessions are needed compared to Q-switched lasers (e.g., 1-3 sessions)

Consider discussing B12 testing with your vet if your dog has: Had chronic or intermittent diarrhoea for more than a few weeks without a clear resolved cause Lost weight progressively despite adequate food intake Been diagnosed with a chronic gut condition, such as inflammatory bowel disease or exocrine pancreatic insufficiency A history of poor early nutrition, such as a recently rescued stray or previously malnourished dog Been through multiple courses of treatment for digestive symptoms without sustained improvement A young dog or puppy that is not developing or gaining weight as expected Causes of Vitamin B12 Deficiency in Dogs Vitamin B12 deficiency in dogs is almost always caused by a problem with absorption rather than a lack of B12 in the diet

Abbreviations CK: Creatine kinase DIP: l-alanyl-l-glutamine GABA: -Aminobutyrate GSH: Glutathione HSE: Heat shock element HSF: Heat shock factor HSP: Heat shock proteins HSP70: 70-kDa protein family IL: Interleukin LDH: Lactate dehydrogenase LIF: Leukaemia inhibitory factor MCP: Monocyte chemotactic protein MDC: Chemokine derived from macrophage PepT: Intestinal transporter ROS: Reactive oxygen species SLC: Solute carrier TNF: Tumour necrosis factor uPA: Fractalkine and urokinase plasminogen activator VEGF: Vascular endothelial growth factor References Newsholme P, Procopio J, Lima MM, Pithon-Curi TC, Curi R

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